ZF900 Total Migration & Non-Volatile Matter Tester

Product Introduction

ZF900 Total Migration & Non-Volatile Matter Tester adopts an integrated system design of water bath evaporation, heating drying, cooling and constant temperature weighing. It is suitable for testing total migration (non-volatile matter, evaporation residue) in purified water, pharmaceutical packaging materials, food packaging, cigarette tipping paper, chemical reagents and other fields. It can also be applied to moisture content and loss-on-drying tests of solid samples, as well as total dissolved solids testing in water quality detection.

Test Principle

The evaporation cups in the test chamber are heated, cooled and weighed according to the set temperature, and the steps are repeated until the constant weight value is reached. Pour the test solution into the evaporation cup, evaporate via water bath heating, heat the cavity to 105℃ for drying, then cool down. After the evaporation dish is cooled, the balance judges the constant weight. The experiment terminates when the constant weight requirement of the test item is satisfied.

Principle Schematic Diagram

Applicable Standards

• Purified Water: Purified Water in Chinese Pharmacopoeia Volume II, EP9.0 WATER, PURIFIED
• Pharmaceutical Packaging Materials: Non-volatile matter items in dissolution test specified in National Pharmaceutical Packaging Material Standards
• Food Contact Materials: GB 31604.8-2021, EN 1186-3:2002 method A, Standards and Specifications for Utensils, Containers and Packages of Korea Ministry of Health and Welfare chapter IV 2-8
• Cigarette Tipping Paper: YQ/T 59-2015
• Chemical Reagents: GB/T 9740-2008, ISO 759
• Water Quality Testing: GB 8538-2016, DZT0064.9-2021, GB/T 14415-2007, GB/T 5750.4-2006
• Solid Samples: "Extractables" and "Loss on Drying" items in Chinese Pharmacopoeia Part IV, USP40-NF35 <921> WATER DETERMINATION

Technical Parameters

Product Features

• Cold-hot dual-chamber integrated control system, upgraded automation

  The integrated system design realizes water bath evaporation, drying, cooling, constant weight measurement and reagent recovery. It effectively avoids the influence of external environment on experiments and makes testing automatic, efficient and precise. Built-in water bath in the chamber adopts liquid level sensor for automatic water level detection, automatic water filling, refilling and draining, as well as automatic water bath temperature control. Multiple safety designs fully guarantee safe handling of water temperature, bath water and waste liquid discharge. Temperature control: Adopts internationally advanced electromagnetic temperature control technology to automatically heat and cool with temperature accuracy of ±0.5℃.

• High-precision imported balance with isolation protection design

  One high-precision imported balance is built in the chamber, and 2 rounds of drying procedures can reach constant weight of 0.3 mg. The balance is placed in a stable protective cover with water circulation interlayer. During evaporation and drying, the balance is completely isolated from the test chamber. The temperature and humidity stay stable during weighing. Weighing data is stable and reliable with good repeatability.

• High throughput and wide applicability for test requirements

  The instrument is equipped with 9 independent test stations with separate data, which meets high-throughput testing requirements and improves test efficiency. Test samples include purified water, organic solvents such as n-hexane, ethanol, acetic acid, chloroform, as well as solid samples and powders.

• Cooling & recovery system for efficient solvent recovery

  Built-in circulating water cooling pump continuously supplies circulating water to keep the chamber at low temperature. The large cooling water tank can rapidly cool down the chamber. Circulating water cooling is efficient and environmentally friendly, cooling to room temperature within 30 minutes. Equipped with solvent recovery bottle, solvent recovery rate exceeds 90%.

• Elegant appearance, convenient operation and real-time visual curve display

  The product appearance is designed from ergonomics and technical aesthetics, adopting gray main tone with Klein blue color lines. Visual test chamber window allows real-time observation of testing process. Fully automatic operation, one-click test, automatic judgment and automatic stop. Real-time display of weighing data, temperature curve and humidity curve; temperature, humidity and weighing data are saved in real time for easy query.

• Intelligent operating system with global certifications

  Self-developed intelligent operating system with modular icons, fashionable color scheme and humanized settings for intuitive and convenient operation. Designed in accordance with GMP appendix for computerized systems, test parameters can be flexibly set to meet different standard requirements. Audit trail function (log tracking, test tracking) supports data traceability. Multi-level operation authority can be configured for the system. Customizable test reports, multiple data output formats, electronic signature and online report review submission. Global certifications, Chinese / English language switch available on demand.

• Laboratory intelligent IoT platform

  The instrument can connect to IoT platform for network digital management. Remote login to IoT platform with authorized access to instrument software interface, realizing experimental data management and remote fault diagnosis. Customers can download instrument documents, manuals and operation videos from the platform by themselves.

Application

	Purified water	Applicable to the test of non-volatile content in purified water and sterile water for injection in the pharmaceutical industry.
	Drug packaging material	It is suitable for the test of non-volatile items in the dissolution test of plastic and rubber pharmaceutical packaging materials
	Food contact material	It is suitable for various food utensils, containers and food packaging films, cans or other food tools, pipes and other products made of polyethylene, polystyrene, polypropylene, perchlorethylene resin as raw materials in different food simulants Determination of total migration after immersion.
	Cigarette pack material	Applicable to the total migration test of the soaking liquid of cigarette tipping paper.
	Chemical reagent	Suitable for chemical reagents, such as ethanol, acetic acid, n-hexane, chloroform and other organic solvents with a boiling point below 100 °C for evaporation residue testing.
	Domestic water and drinking water, industrial water, sewage	It is suitable for the total dissolved solids test of domestic drinking water, drinking natural mineral water, ground water, drinking water, swimming pool water, urban sewage, industrial boiler water, etc.
	Solid samples, pharmaceutical particles	Applicable to solid samples, such as empty capsules, microcrystalline cellulose and other medicines, or other solid particles for loss on drying, dryness or moisture testing.